Optometry 2004;75:216-30. View abstract. 2011;52(11):8174-8178. Eur.J Clin.Nutr. View abstract. Some might have a harder time utilizing it and other antioxidants from foods and transporting to tissues within the eyes or other organs. 2004;3(6):310-316. Li, L., Chen, C. Y., Aldini, G., Johnson, E. J., Rasmussen, H., Yoshida, Y., Niki, E., Blumberg, J. Br J Ophthalmol 1998;82:907-10. Biosci Biotechnol Biochem 2019;83(12):2372-4. View abstract. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. 2011;24 Suppl 1:147-150. View abstract. View abstract. Wright, A. J., Hughes, D. A., Bailey, A. L., and Southon, S. Beta-carotene and lycopene, but not lutein, supplementation changes the plasma fatty acid profile of healthy male non-smokers. Am J Clin Nutr 2003;78(5):985-992. View abstract. Invest Ophthalmol.Vis.Sci. Li J, Abdel-Aal EM. View abstract. Invest Ophthalmol Vis Sci 1995;36:276-88. Valero, M. P., Fletcher, A. E., De Stavola, B. L., Vioque, J., and Alepuz, V. C. Vitamin C is associated with reduced risk of cataract in a Mediterranean population. 2001;42(8):1873-1881. Berendschot, T. T., Goldbohm, R. A., Klopping, W. A., van de, Kraats J., van Norel, J., and van Norren, D. Influence of lutein supplementation on macular pigment, assessed with two objective techniques. Ito, Y., Wakai, K., Suzuki, K., Tamakoshi, A., Seki, N., Ando, M., Nishino, Y., Kondo, T., Watanabe, Y., Ozasa, K., and Ohno, Y. Serum carotenoids and mortality from lung cancer: a case-control study nested in the Japan Collaborative Cohort (JACC) study. Arch.Ophthalmol. 2008;27(2):218-227. Chopra, M., O'Neill, M. E., Keogh, N., Wortley, G., Southon, S., and Thurnham, D. I. Maternal lutein and zeaxanthin concentrations in relation to offspring visual acuity at 3 years of age: The GUSTO Study. Chew EY, Clemons TE, Agrn E, et al. A. Am J Epidemiol 1999;149:801-9. Retina 2010;30(8):1282-1293. JAMA 1994;272:1413-20. 2014;42(1):25-38. 2010;9:22. Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial. Int.J.Vitam.Nutr.Res. Lutein has earned the nickname the eye vitamin because itswell-known for protecting eye health. San Giovanni, J. P., Chew, E. Y., Clemons, T. E., Ferris, F. L., III, Gensler, G., Lindblad, A. S., Milton, R. C., Seddon, J. M., and Sperduto, R. D. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. Front Aging Neurosci 2017;9:254. 2014 Jan 22;6(1):452-65. Dietary intake of antioxidants and risk of age-related macular degeneration. Astaxanthin supplementation does not attenuate muscle injury following eccentric exercise in resistance-trained men. Beatty, S., Murray, I. J., Henson, D. B., Carden, D., Koh, H., and Boulton, M. E. Macular pigment and risk for age-related macular degeneration in subjects from a Northern European population. Are supplements really necessary to achieve benefits? 2003;94(1):57-63. View abstract. Epidemiology. View abstract. View abstract. 2008;32(2):351-353. Lyle BJ, Mares-Perlman JA, Klein BE, et al. Edwards CG, Walk AM, Thompson SV, et al. A., Klein, M. L., Gehrs, K. M., Johnson, E. J., Snodderly, D. M., Wallace, R. B., Chappell, R. J., Parekh, N., Ritenbaugh, C., and Mares, J. 2013;73(2):236-45. Sadly, the incidence of AMD is expected to triple by 2025, according to the American Optometric Association. 2000;46(11):1818-1829. B., Xu, X. R., Zou, Z. Y., and Lin, X. M. Lutein and zeaxanthin intake and the risk of age-related macular degeneration: a systematic review and meta-analysis. Castenmiller, J. J., Lauridsen, S. T., Dragsted, L. O., het Hof, K. H., Linssen, J. P., and West, C. E. beta-carotene does not change markers of enzymatic and nonenzymatic antioxidant activity in human blood. B. Lutein and zeaxanthin concentrations in plasma after dietary supplementation with egg yolk. View abstract. Am.J.Clin.Nutr. This amount can be obtained pretty easily by eating a healthy andhealing diet(one cup of kale has more than22 milligrams), but supplements are also recommended for people who are highly susceptible to eye damage, those who have digestive disorders that can hinder nutrient absorption and the elderly, who could use more protection. Arch Neurol 2000;57:956-63. Eur.J.Clin.Nutr. Int J Vitam.Nutr Res. Brown L, Rimm EB, Seddon JM, et al. Lutein and zeaxanthin intake during pregnancy and visual function in offspring at 11-12 years of age. Intakes of vitamin C and carotenoids and risk of amyotrophic lateral sclerosis: pooled results from 5 cohort studies. View abstract. Ma L, Hao ZX, Liu RR, et al. Although carotenoids are extremely important for vision and your eyes, their benefits dont stop there. Qiu Z, Chen X, Geng T, et al. View abstract. van den Berg H. Effect of lutein on beta-carotene absorption and cleavage. View abstract. View abstract. O'Neill, M. E., Carroll, Y., Corridan, B., Olmedilla, B., Granado, F., Blanco, I., van den, Berg H., Hininger, I., Rousell, A. M., Chopra, M., Southon, S., and Thurnham, D. I. Lutein supplements have been used safely by adults in doses up to 15 to 20 milligrams daily for as long as two years without any serious side effects. With dry eye disease, also known as dry eye syndrome, your eyes dont make enough lubrication to coat your eyes. This can cause red, itchy, burning, eyes, temporary blurriness, and a feeling as if theres sand in your eye. According to a 2016 study, lutein may help reduce these symptoms. How much lutein do you need? Seddon JM, Ajani UA, Sperduto RD, et al. Ge XX, Xing MY, Yu LF, et al. View abstract. Williams, M. A., Woelk, G. B., King, I. Richer, S. P., Stiles, W., Graham-Hoffman, K., Levin, M., Ruskin, D., Wrobel, J., Park, D. W., and Thomas, C. Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic age-related macular degeneration: the Zeaxanthin and Visual Function Study (ZVF) FDA IND #78, 973. WebThe best antihistamine for eczema is the one that relieves your symptoms. Invest Ophthalmol.Vis.Sci. Neutrogena Norwegian Formula Dry Hand Cream. 26th ed. 2014 Jan;252(1):63-70. Zinc. Berson, E. L., Rosner, B., Sandberg, M. A., Weigel-DiFranco, C., Brockhurst, R. J., Hayes, K. C., Johnson, E. J., Anderson, E. J., Johnson, C. A., Gaudio, A. R., Willett, W. C., and Schaefer, E. J. View abstract. Takeda A, Nyssen OP, Syed A, et al. View abstract. Ophthalmology 2012;119(11):2290-2297. Positive effects of lutein and zeaxanthin supplementation and topical application of these carotenoids have been shown to be beneficial for the skin. Effects of supplemental beta-carotene , cigarette smoking, and alcohol consumption on serum carotenoids in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. 60 Count (Pack of 1) 4.5 4.5 out of 5 View abstract. Exp Eye Res 2004;79:21-27. View abstract. View abstract. The Effects of Lutein and Zeaxanthin Supplementation on Brain Morphology in Older Adults: A Randomized, Controlled Trial. Am.J.Clin.Nutr. Invest Ophthalmol.Vis.Sci. View abstract. View abstract. 2006;90(7):927-928. View abstract. View abstract. Relationship of serum alpha-tocopherol, carotenoids and retinol with the risk of breast cancer. 1996;66(4):316-321. Mahmassani HA, Switkowski KM, Scott TM, et al. Am.J.Clin.Nutr. Keep in mind that as with other antioxidants, people seem to differ in terms of how capable their bodies are of absorbing lutein. This daily supplementation decreased the risk of macular degeneration from intermediate to advanced stages by 25%. 2012;53(12):7871-7880. Tan, J. S., Wang, J. J., Flood, V., Rochtchina, E., Smith, W., and Mitchell, P. Dietary antioxidants and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study. Ophthalmol Sci 2021;1(3):100039. Med Hypotheses 1983;12:239-51. View abstract. J Am Coll Nutr 2019;38(2):179-184. Intestinal absorption, serum clearance, and interactions between lutein and beta-carotene when administered to human adults in separate or combined oral doses. Am J Clin Nutr 1999;69(2):272-277. Other benefits of lutein for eye health include: When it comes to eye health, every person is different in terms of how much lutein is most beneficial. Clinical trial of lutein in patients with retinitis pigmentosa receiving vitamin A. Arch.Ophthalmol. 2000;41(5):1200-1209. 2012;56(1):126-146. Wilson LM, Tharmarajah S, Jia Y, Semba RD, Schaumberg DA, Robinson KA. Palombo, P., Fabrizi, G., Ruocco, V., Ruocco, E., Fluhr, J., Roberts, R., and Morganti, P. Beneficial long-term effects of combined oral/topical antioxidant treatment with the carotenoids lutein and zeaxanthin on human skin: a double-blind, placebo-controlled study. Cancer Causes Control 1991;2:325-57. View abstract. Int J Sport Nutr Exerc Metab 2005;15:401-12. Invest Ophthalmol Vis Sci. Anderson MJ, Romaguera D, Saint-Amour D, et al. are clickable links to medically peer-reviewed studies. View abstract. Sin, H. P., Liu, D. T., and Lam, D. S. Lifestyle modification, nutritional and vitamins supplements for age-related macular degeneration. Incidence of cataract operations in Finnish male smokers unaffected by alpha tocopherol or beta carotene supplements. View abstract. You already know that filling up on plenty of fruits and veggies is good for you, and heres just another example of why that is. Ros, M. M., Bueno-de-Mesquita, H. B., Kampman, E., Aben, K. K., Buchner, F. L., Jansen, E. H., van Gils, C. H., Egevad, L., Overvad, K., Tjonneland, A., Roswall, N., Boutron-Ruault, M. C., Kvaskoff, M., Perquier, F., Kaaks, R., Chang-Claude, J., Weikert, S., Boeing, H., Trichopoulou, A., Lagiou, P., Dilis, V., Palli, D., Pala, V., Sacerdote, C., Tumino, R., Panico, S., Peeters, P. H., Gram, I. T., Skeie, G., Huerta, J. M., Barricarte, A., Quiros, J. R., Sanchez, M. J., Buckland, G., Larranaga, N., Ehrnstrom, R., Wallstrom, P., Ljungberg, B., Hallmans, G., Key, T. J., Allen, N. E., Khaw, K. T., Wareham, N., Brennan, P., Riboli, E., and Kiemeney, L. A. Another convincing factor is that after the researchers tested effects of the carotenoid on human arteries that wereremoved during surgery, fewer white cells were present within the arteries after lutein supplementation compared to controls, suggesting that less inflammation and clogging occurred. View abstract. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Eur J Clin Nutr 2007;61:1167-73. Epidemiology 2004;15(6):738-745. Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease. View abstract. J.Nutr. Dietary carotenoid intake and risk of developing preeclampsia: a hospital-based case-control study. Cho, E., Hankinson, S. E., Rosner, B., Willett, W. C., and Colditz, G. A. Kotagiri SR, Morde A, Rai D, et al. Bates, C. J., Chen, S. J., Macdonald, A., and Holden, R. Quantitation of vitamin E and a carotenoid pigment in cataractous human lenses, and the effect of a dietary supplement. Skinmed. Siems, W. G., Sommerburg, O., and van Kuijk, F. J. Lycopene and beta-carotene decompose more rapidly than lutein and zeaxanthin upon exposure to various pro-oxidants in vitro. Baltimore, MD: Williams & Wilkins, 1995. Arterioscler.Thromb.Vasc.Biol 2004;24(2):313-319. View abstract. View abstract. Richer S, Stiles W, Statkute L, et al. 1997;78(5):775-784. View abstract. Lee EH, Faulhaber D, Hanson KM, et al. Nutr Neurosci 2021. Neonatology. Xu J, Song C, Song X, Zhang X, Li X. Carotenoids and risk of fracture: a meta-analysis of observational studies. View abstract. View abstract. Skin Pharmacol.Physiol 2007;20(4):199-210. PLoS One 2019;14(12):e0227048. Herron, K. L., McGrane, M. M., Waters, D., Lofgren, I. E., Clark, R. M., Ordovas, J. M., and Fernandez, M. L. The ABCG5 polymorphism contributes to individual responses to dietary cholesterol and carotenoids in eggs. This includes a 2018 study in which researchers concluded: Dietary lutein supplementation may be a promising alternative and/or adjunct therapeutic candidate against breast cancer.. View abstract. 2000;9(3):257-263. It's related to beta-carotene and vitamin A. Lutein-rich foods include egg yolks, broccoli, spinach, kale, corn, orange pepper, kiwi fruit, grapes, orange juice, zucchini and squash. J Nutr 2004;134:2387-94. Chew EY, Clemons TE, Agrn E, et al . Gossage C, Deyhim M, Moser-Veillon PB, et al. Effects of lutein and docosahexaenoic Acid supplementation on macular pigment optical density in a randomized controlled trial. 1998;7(6):537-544. Association between intake of antioxidants and pancreatic cancer risk: a meta-analysis. Yeum, K. J., Booth, S. L., Sadowski, J. View abstract. Ann Neurol. Ma, L., Lin, X. M., Zou, Z. Y., Xu, X. R., Li, Y., and Xu, R. A 12-week lutein supplementation improves visual function in Chinese people with long-term computer display light exposure. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Intakes of Lutein, Zeaxanthin, and Other Carotenoids and Age-Related Macular Degeneration During 2 Decades of Prospective Follow-up. Am.J.Clin.Nutr. Clin Chem 2007;53(3):447-455. 3-1-2001;153(5):424-432. View abstract. Exp.Eye Res. van Leeuwen R, Boekhoorn S, Vingerling JR, et al. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. 2009;102(2):186-190. J.Ocul.Pharmacol.Ther. Cancer Epidemiol.Biomarkers Prev. Mares-Perlman JA, Brady WE, Klein BE, et al. Biomed Res 2011;32(6):387-393. Goodman, M. T., Kiviat, N., McDuffie, K., Hankin, J. H., Hernandez, B., Wilkens, L. R., Franke, A., Kuypers, J., Kolonel, L. N., Nakamura, J., Ing, G., Branch, B., Bertram, C. C., Kamemoto, L., Sharma, S., and Killeen, J. Ophthalmologica 2017;237(3):159-66. Prog Retin Eye Res. Ophthalmic Res. Ophthalmol Ther 2022;11(4):1463-1477. Rosenthal, J. M., Kim, J., de, Monasterio F., Thompson, D. J., Bone, R. A., Landrum, J. T., de Moura, F. F., Khachik, F., Chen, H., Schleicher, R. L., Ferris, F. L., III, and Chew, E. Y. Dose-ranging study of lutein supplementation in persons aged 60 years or older. Mares-Perlman, J. View abstract. View abstract. An ancillary study of the women's health initiative. J Nutr 1997;127:1636S-45S. 2012;96(5):1223S-1233S. WebShop 12 Hour Mucus Relief DM Extended-Release Tablets Maximum Strength and read reviews at Walgreens. View abstract. View abstract. Diet and lifestyle correlates of lutein in the blood and diet. Nutrients 2022;14(4):872. Am J Epidemiol 2007;165(3):246-55. View abstract. The pharmacological effects of quercetin, such as its antioxidant, anti-inflammatory, antiallergic, antiaging, and anticancer activities, as well as its regulating effect on interleukin (IL)-6, IL-8, tumor necrosis factor (TNF), histamine, and tryptase release in mast cells, are well acknowledged [9]. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. View abstract. 2004;80(1):131-136. View abstract. Abnet, C. C., Qiao, Y. L., Dawsey, S. M., Buckman, D. W., Yang, C. S., Blot, W. J., Dong, Z. W., Taylor, P. R., and Mark, S. D. Prospective study of serum retinol, beta-carotene, beta-cryptoxanthin, and lutein/zeaxanthin and esophageal and gastric cancers in China. Invest Ophthalmol.Vis.Sci. View abstract. Feng L, Nie K, Jiang H, Fan W. Effects of lutein supplementation in age-related macular degeneration. Ophthalmology 2012;119(11):2282-2289. Ophthalmology 2011;118(10):1958-1965. Ma, L., Dou, H. L., Huang, Y. M., Lu, X. R., Xu, X. R., Qian, F., Zou, Z. Y., Pang, H. L., Dong, P. C., Xiao, X., Wang, X., Sun, T. T., and Lin, X. M. Improvement of retinal function in early age-related macular degeneration after lutein and zeaxanthin supplementation: a randomized, double-masked, placebo-controlled trial. 8-15-2012;92(10):2043-2049. View abstract. View abstract. JAMA 2005;294:3101-7. View abstract. Central retinal thickness is positively correlated with macular pigment optical density. 2011;94(5):1211-1218. View abstract. WebCommon drugs people take besides Lutein *: Dupixent: 2 people, 18.18%. This is why we need antioxidants to help neutralize free radicals. Kawabata, F. and Tsuji, T. Effects of dietary supplementation with a combination of fish oil, bilberry extract, and lutein on subjective symptoms of asthenopia in humans. Am J Clin Nutr 2006;83(1):163-169. 2002;120(12):1732-1737. View abstract. View abstract. Int J Food Sci Nutr 2016;67(7):744-53. Astaxanthin is a red pigment that belongs to a group of chemicals called carotenoids. Am J Clin Nutr 2000;71:950-5. Chasan-Taber L, Willett WC, Seddon JM, et al. 2014;52(4):198-205. View abstract. View abstract. Nutrient intake and cataract extraction in women: a prospective study. View abstract. are clickable links to these studies. When taken in high doses, potential lutein side effects can includeharmless yellowing of the skin called carotenemia or vomiting, although these are rare. WebLutein is a type of vitamin that is called carotenoid. J Natl.Cancer Inst. 2017;7:CD000254. View abstract. However, most studies show that benefits are greatest when someone consumes 10 milligrams of lutein per day or more (along with about two milligrams of zeaxanthin perday). Vallverdu-Queralt, A., Martinez-Huelamo, M., Arranz-Martinez, S., Miralles, E., and Lamuela-Raventos, R. M. Differences in the carotenoid content of ketchups and gazpachos through HPLC/ESI(Li(+) )-MS/MS correlated with their antioxidant capacity. At this time there isnt a general recommendation for daily intake of lutein or zeaxanthin. View abstract. Acta Ophthalmol.Scand. Nutrients. People who dont eat many vegetable or fruits can probably benefit from supplementing with higher doses, as can older adults, smokers and post-menopausal women. J Nutr.Biochem. Correlation between carotenoid concentrations in serum and normal breast adipose tissue of women with benign breast tumor or breast cancer. J.Nutr. Ma, L., Yan, S. F., Huang, Y. M., Lu, X. R., Qian, F., Pang, H. L., Xu, X. R., Zou, Z. Y., Dong, P. C., Xiao, X., Wang, X., Sun, T. T., Dou, H. L., and Lin, X. M. Effect of lutein and zeaxanthin on macular pigment and visual function in patients with early age-related macular degeneration. Some evidence shows that people who obtain more lutein from their diets experience lower rates of breast, colon, cervical and lung cancers. View abstract. There's 44 mg of lutein in one cup of cooked kale, 26 mg per cup of cooked spinach, and 3 mg per cup of broccoli. Goltz, S. R., Campbell, W. W., Chitchumroonchokchai, C., Failla, M. L., and Ferruzzi, M. G. Meal triacylglycerol profile modulates postprandial absorption of carotenoids in humans. Overall skin tone and skin-lightening-improving effects with oral supplementation of lutein and zeaxanthin isomers: a double-blind, placebo-controlled clinical trial. Dietary lutein reduces ultraviolet radiation-induced inflammation and immunosuppression. J Nutr 2022;152(11):2555-64. 2006;47(12):5227-5233. Dherani, M., Murthy, G. V., Gupta, S. K., Young, I. S., Maraini, G., Camparini, M., Price, G. M., John, N., Chakravarthy, U., and Fletcher, A. E. Blood levels of vitamin C, carotenoids and retinol are inversely associated with cataract in a North Indian population. 80 mg of zinc. A possible role for lutein and zeaxanthin in cognitive function in the elderly. Serum antioxidants and age-related macular degeneration in a population-based case-control study. Ophthalmology 2003;110(1):51-60. Cancer Sci. View abstract. The average person who eats the standard American diet is likely running low in this carotenoid, in addition to other important antioxidants. View abstract. Leermakers ET, Darweesh SK, Baena CP, et al. Paetau, I., Rao, D., Wiley, E. R., Brown, E. D., and Clevidence, B. Plasma and macular responses to lutein supplement in subjects with and without age-related maculopathy: a pilot study. Duncan, J. L., Aleman, T. S., Gardner, L. M., De Castro, E., Marks, D. A., Emmons, J. M., Bieber, M. L., Steinberg, J. D., Bennett, J., Stone, E. M., MacDonald, I. M., Cideciyan, A. V., Maguire, M. G., and Jacobson, S. G. Macular pigment and lutein supplementation in choroideremia. Chen J, Jiang W, Shao L, Zhong D, Wu Y, Cai J. Am J Epidemiol 1998;148:204-14. WebIf your eczema ( atopic dermatitis) flare-ups are really bad, oral corticosteroids are one of the treatment options that can help soothe your irritated skin. Garcia-Closas, R., Agudo, A., Gonzalez, C. A., and Riboli, E. Intake of specific carotenoids and flavonoids and the risk of lung cancer in women in Barcelona, Spain. Eye Disease Case-Control Study Group. View abstract. A., Hollenbach, K. A., Newman, V. A., Faerber, S., Ritenbaugh, C. K., Gold, E., Stefanick, M. L., Jones, L. A., Marshall, J. R., and Pierce, J. P. On the importance of using multiple methods of dietary assessment. Ophthalmology 2008;115(2):334-341. J Matern Fetal Neonatal Med 2020:1-6. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Nolan JM, Power R, Howard AN, et al. Cardinault, N., Gorrand, J. M., Tyssandier, V., Grolier, P., Rock, E., and Borel, P. Short-term supplementation with lutein affects biomarkers of lutein status similarly in young and elderly subjects. View abstract. While the research is still in its early stages, taking lutein three times weekly for up to two years has been shown to improve vision in older people who already have cataracts. Arch Ophthalmol 1995;113:518-23. Breast Cancer Res.Treat. Invest Ophthalmol.Vis.Sci. Upritchard, J. E., Schuurman, C. R., Wiersma, A., Tijburg, L. B., Coolen, S. A., Rijken, P. J., and Wiseman, S. A. Thurnham, D. I., Northrop-Clewes, C. A., Paracha, P. I., and McLoone, U. J. Relation between dietary intake, serum concentrations, and retinal concentrations of lutein and zeaxanthin in adults in a Midwest population. Sommerburg O, Keunen JE, Bird AC, van Kuijk FJ. There arent any known special precautions for women who are pregnant or breastfeeding, but its always a good idea to speak with your doctor when pregnant before beginning new supplemental treatments. View abstract. An eye disorder in premature infants that can lead to blindness (retinopathy of prematurity). View abstract. Schunemann HJ, Grant BJ, Freudenheim JL, et al. Am J Clin Nutr 2012;96(4):902-910. Nicknamed the eye vitamin, lutein is a type of carotenoid antioxidant that is most well-known for protecting eye health. Hozawa, A., Jacobs, D. R., Jr., Steffes, M. W., Gross, M. D., Steffen, L. M., and Lee, D. H. Relationships of circulating carotenoid concentrations with several markers of inflammation, oxidative stress, and endothelial dysfunction: the Coronary Artery Risk Development in Young Adults (CARDIA)/Young Adult Longitudinal Trends in Antioxidants (YALTA) study. Nutr.Rev. Nutr.J. Br J Nutr 2004;92(1):113-118. Parisi V, Tedeschi M, Gallinaro G, et al. View abstract. 2013 Jan;30(1):25-32. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. van der Horst-Graat JM, Kok, F. J., and Schouten, E. G. Plasma carotenoid concentrations in relation to acute respiratory infections in elderly people. View abstract. Br.J.Nutr. 2003;42(6):315-323. The relation of serum levels of antioxidant vitamins C and E, retinol and carotenoids with pulmonary function in the general population. View abstract. Bone, R. A., Landrum, J. T., Dixon, Z., Chen, Y., and Llerena, C. M. Lutein and zeaxanthin in the eyes, serum and diet of human subjects. Glucosamine: 2 people, 18.18%. Plasma kinetics of lutein, zeaxanthin, and 3-dehydro-lutein after multiple oral doses of a lutein supplement. View abstract. 2001;55(4):252-259. View abstract. View abstract. By performing a macular pigment optical density test (MPOD), doctors can better give specialized dietary recommendations for protective nutrients based on individual responses, genetic predisposition and lifestyle factors. Estimates show that more than 25 million people worldwide are affected by age-related macular degeneration or cataracts, especially people aged 55 and older living in industrialized Western nations. Dreher, M. L. Pistachio nuts: composition and potential health benefits. Likely not, but overall we still have a way to go when it comes to understanding the full potential of lutein in terms of disease prevention, bioavailability, metabolism and dose-response relationships. Ferguson, L. R. and Schlothauer, R. C. The potential role of nutritional genomics tools in validating high health foods for cancer control: broccoli as example. Olmedilla, B., Granado, F., Blanco, I., and Vaquero, M. Lutein, but not alpha-tocopherol, supplementation improves visual function in patients with age-related cataracts: a 2-y double-blind, placebo-controlled pilot study. 2008;126(3):354-364. Bone, R. A., Landrum, J. T., Guerra, L. H., and Ruiz, C. A. Lutein and zeaxanthin dietary supplements raise macular pigment density and serum concentrations of these carotenoids in humans. This eye vitamin isnt just beneficial for older adults taking preventative measures is the real key to preserving your vision and eye health. Yamini, S., West, K. P., Jr., Wu, L., Dreyfuss, M. L., Yang, D. X., and Khatry, S. K. Circulating levels of retinol, tocopherol and carotenoid in Nepali pregnant and postpartum women following long-term beta-carotene and vitamin A supplementation. Antioxidant intake and risk of incident age-related nuclear cataracts in the Beaver Dam Eye Study. Front Nutr 2022;9:843512. Sasamoto, Y., Gomi, F., Sawa, M., Tsujikawa, M., and Nishida, K. Effect of 1-year lutein supplementation on macular pigment optical density and visual function. Optometry. A., and Guymer, R. H. Dietary antioxidants and primary prevention of age related macular degeneration: systematic review and meta-analysis. View abstract. Association between lutein and zeaxanthin status and the risk of cataract: a meta-analysis. 2013;54(1):476-481. View abstract. Gale, C. R., Hall, N. F., Phillips, D. I., and Martyn, C. N. Plasma antioxidant vitamins and carotenoids and age-related cataract. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. JAMA 2013;309(19):2005-2015. Hajizadeh-Sharafabad F, Tarighat-Esfanjani A, Ghoreishi Z, Sarreshtedari M. Lutein supplementation combined with a low-calorie diet in middle-aged obese individuals: effects on anthropometric indices, body composition and metabolic parameters. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Olmedilla B, Granado F, Southon S, et al. A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa. View abstract. Loughman J, Loskutova E, Butler JS, Siah WF, O'Brien C. Macular pigment response to lutein, zeaxanthin, and meso-zeaxanthin supplementation in open-angle glaucoma: A randomized controlled trial. J Lab Clin Med 1999;134(6):592-598. View abstract. View abstract. View abstract. View abstract. Liver Cleanse | Lutein Benefits, Uses, Foods, Side Effects and More - Dr View abstract. View abstract. J Am Coll Nutr 2001;20(3):232-238. View abstract. Am.J.Clin.Nutr. 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